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Frank H de Jong Selected Research

Metyrapone

1/2019Osilodrostat Is a Potential Novel Steroidogenesis Inhibitor for the Treatment of Cushing Syndrome: An In Vitro Study.
7/2009The relationship between central adrenal insufficiency and sleep-related breathing disorders in children with Prader-Willi syndrome.
11/2005Expression of the human glucocorticoid receptor splice variants alpha, beta, and P in peripheral blood mononuclear leukocytes in healthy controls and in patients with hyper- and hypocortisolism.

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Frank H de Jong Research Topics

Disease

6Cushing Syndrome
01/2021 - 01/2003
6Prostatic Neoplasms (Prostate Cancer)
11/2013 - 02/2005
6Neoplasms (Cancer)
01/2013 - 02/2010
5Atherosclerosis
03/2014 - 08/2002
5Insulin Resistance
05/2012 - 10/2002
4Cardiovascular Diseases (Cardiovascular Disease)
08/2015 - 08/2002
4Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
06/2014 - 04/2008
4Adrenocortical Carcinoma
09/2013 - 02/2012
4Cognitive Dysfunction
01/2009 - 02/2003
346,XY Disorder of Sex Development (Male Pseudohermaphroditism)
01/2016 - 03/2010
3Infertility (Sterility)
03/2015 - 09/2004
3Adenoma (Adenomas)
01/2015 - 01/2003
3Virilism (Virilization)
04/2013 - 11/2009
3Hyperplasia
05/2012 - 01/2003
3Sepsis (Septicemia)
07/2009 - 09/2005
3Dementia (Dementias)
05/2008 - 05/2003
2Pituitary Neoplasms (Pituitary Adenoma)
01/2021 - 01/2019
2Cryptorchidism (Undescended Testes)
08/2017 - 04/2014
2Gonadal Dysgenesis (Gonadal Agenesis)
01/2016 - 01/2012
2Hypertension (High Blood Pressure)
08/2015 - 01/2015
2Diabetes Mellitus
08/2015 - 11/2002
2Adrenal Insufficiency (Adrenal Gland Hypofunction)
05/2012 - 09/2005
2Prader-Willi Syndrome (Syndrome, Prader-Willi)
03/2012 - 07/2011
2Type 2 Diabetes Mellitus (MODY)
01/2012 - 04/2011
2Chronic Disease (Chronic Diseases)
01/2012 - 05/2003
2Osteoporosis
10/2011 - 08/2005
2Septic Shock (Toxic Shock Syndrome)
07/2009 - 09/2005
2Glucocorticoid Receptor Deficiency
05/2008 - 08/2004
2Myocardial Infarction
01/2008 - 06/2004
2Hodgkin Disease (Hodgkin's Disease)
12/2007 - 10/2007
2Hypersensitivity (Allergy)
02/2006 - 11/2003
2Alzheimer Disease (Alzheimer's Disease)
05/2003 - 02/2003
1ACTH-Secreting Pituitary Adenoma
01/2021
1XX Disorders of Sex Development 46 (Female Pseudohermaphroditism)
01/2016
1Sex Chromosome Disorders of Sex Development
01/2016
1Anovulation
03/2015
1Atrial Fibrillation
03/2014
1Adrenal Cortex Neoplasms (Adrenocortical Cancer)
01/2014
1Acth-Independent Macronodular Adrenal Hyperplasia
09/2013
1Leydig Cell Tumor
04/2013
1Neoplasm Metastasis (Metastasis)
12/2012
1Rheumatoid Arthritis
08/2012
1Carcinogenesis
08/2012

Drug/Important Bio-Agent (IBA)

15AndrogensIBA
01/2016 - 08/2002
13Hydrocortisone (Cortisol)FDA LinkGeneric
09/2013 - 01/2003
12Hormones (Hormone)IBA
03/2015 - 08/2002
9Testosterone (Sustanon)FDA Link
08/2017 - 08/2002
7Adrenocorticotropic Hormone (ACTH)FDA Link
01/2021 - 01/2003
7inhibin BIBA
08/2017 - 04/2007
7GlucocorticoidsIBA
08/2012 - 11/2003
6Estradiol (Delestrogen)FDA LinkGeneric
08/2015 - 05/2003
6EnzymesIBA
09/2013 - 02/2010
5Messenger RNA (mRNA)IBA
01/2015 - 01/2003
4SteroidsIBA
01/2021 - 01/2008
4Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
07/2009 - 08/2004
3Ketoconazole (Nizoral)FDA LinkGeneric
01/2021 - 05/2010
3MetyraponeFDA Link
01/2019 - 11/2005
3AldosteroneIBA
01/2015 - 09/2005
3Dehydroepiandrosterone SulfateIBA
03/2014 - 08/2002
3Inhibins (Inhibin)IBA
09/2013 - 02/2012
3activin AIBA
09/2013 - 09/2007
3Dehydroepiandrosterone (DHEA)IBA
09/2013 - 12/2010
3Biomarkers (Surrogate Marker)IBA
02/2012 - 10/2007
3Anti-Mullerian HormoneIBA
11/2009 - 10/2007
3C-Reactive ProteinIBA
01/2008 - 07/2006
2Oxidoreductases (Dehydrogenase)IBA
01/2015 - 01/2013
2Angiotensin IIIBA
01/2015 - 09/2013
2Androgen Receptors (Androgen Receptor)IBA
11/2013 - 01/2012
2Proteins (Proteins, Gene)FDA Link
09/2013 - 04/2011
2Dexamethasone (Maxidex)FDA LinkGeneric
01/2013 - 07/2006
2FollistatinIBA
12/2012 - 09/2007
2Activins (Activin)IBA
12/2012 - 08/2012
2Gonadal Steroid Hormones (Sex Hormones)IBA
01/2012 - 01/2009
2GonadotropinsIBA
08/2011 - 06/2011
2Follicle Stimulating Hormone (Follitropin)FDA Link
08/2011 - 04/2007
2Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA
03/2010 - 02/2004
2ReninIBA
11/2009 - 09/2005
2Interleukin-6 (Interleukin 6)IBA
01/2008 - 09/2005
2EtomidateFDA LinkGeneric
01/2008 - 09/2005
2Glucose (Dextrose)FDA LinkGeneric
01/2007 - 11/2002
2LDL CholesterolIBA
08/2004 - 10/2002
2Estrogens (Estrogen)FDA Link
06/2004 - 02/2003
1OsilodrostatIBA
01/2019
1Androstenedione (4 Androstene 3,17 dione)IBA
01/2016
117-alpha-Hydroxyprogesterone (17 Hydroxyprogesterone)IBA
01/2016
13 beta-hydroxysteroid dehydrogenase type IIIBA
01/2015
1Oral ContraceptivesIBA
06/2014
1Indicators and Reagents (Reagents)IBA
03/2014
1inhibin-alpha subunitIBA
01/2014
1Protein Kinase CIBA
09/2013
1Arginine Vasopressin (Argipressin)IBA
09/2013
1CatecholaminesIBA
09/2013
1Steroid Receptors (Steroid Receptor)IBA
01/2013
1Peptides (Polypeptides)IBA
08/2012

Therapy/Procedure

5Therapeutics
11/2013 - 05/2003
4Castration
11/2013 - 02/2010
2Drug Therapy (Chemotherapy)
01/2021 - 12/2007
2Combination Drug Therapy (Combination Chemotherapy)
12/2007 - 10/2007
1Orchiopexy
04/2014
1Adrenalectomy
05/2012